About the Study

The purpose of this research study is to determine if different durations of exercise can improve  how well you tolerate chemotherapy for colon cancer.

Your expected time in this study will be approximately the duration of your chemotherapy (usually three to six months), consisting of up to three study visits and approximately 12 or 24 telephone calls (one for each week that you are in the study).

The procedures involved in this study include:

  • Medical history and physical exam
  • Questionnaires
  • Physical fitness measures
  • Sit-and-Reach flexibility test
  • Handgrip strength
  • Dual-energy x-ray absorptiometry (DEXA)
  • Physical activity and sleep measures
  • Height, weight, waist, and hip measures
  • Vital signs
  • Electrocardiogram (ECG or EKG)
  • Lab work
  • Exercise instructions
  • Weekly telephone calls

The study visits will take place at Pennington Biomedical Research Center. Exercise will take place at the participant’s home.

What is a Clinical Study?

Clinical studies show us what is effective in medicine and health care. In a clinical study, volunteers help researchers look at new ways to prevent, detect, or treat conditions. They take place in doctors’ offices, medical centers, community hospitals and clinics, and veterans’ hospitals around the world. 

Before a treatment can be approved for everyday use and made accessible to most patients, the U.S. FDA requires that a potential therapy’s safety and efficacy be evaluated in clinical studies. Clinical studies do not just study new drugs — they also help improve treatments already given to patients. 

Who Can Participate?

You may be eligible to participate in the ACTION research study if you:

  • Are age ≥18 years
  • Have been diagnosed with colon cancer that is stage II or III
  • Have completed surgery for colon cancer
  • Will begin chemotherapy for colon cancer
  • Are not participating in extensive regular exercise
  • Provide written physician approval for participation
  • Allow the collection and storage of biospecimens, imaging, and data for future use
  • Are willing to be randomized and are willing to participate in physical activity
  • Can read and speak English
  • Can walk 1 to 2 city blocks or 1 lap around the track without help from another person, walker, or cane

You may not qualify for this study based on other eligibility criteria not listed. The study coordinator will go over this information in detail.

Participants will be paid up to $200 for study participation. You will also receive a treadmill at no cost to you that is yours to keep at the end of the study.

Who Can Participate?

If you are interested in learning more about the ACTION study and if it may be a good fit for you, please submit the short questionnaire. The answers you submit will be used for study purposes only.

Once you submit the form, a member from our team will reach out to you and connect you with a member of the research team if it seems you may qualify for this study.

Please note that answering these questions does not obligate you to participate in the study. If you have any questions, simply email [email protected] or call 1-888-874-2560.