High cholesterol even while taking medications?
Study Overview
The AstraZeneca “AZURE-Outcomes” study is testing a potential new oral, once a day, drug to learn whether it can help lower bad cholesterol and reduce the risk of heart and blood vessel disease in adults who:
- Have a history of heart disease or blood vessel disease OR
- Are at high risk for a first cardiovascular event, such as heart attack, stroke, or circulatory issues in the legs.
Qualified Participants May Receive:
- Reimbursement for their travel
- Study-related care at no cost.
Who Can Participate In The AZURE-Outcomes Study?
People With a Prior Cardiovascular Event:
Are you taking cholesterol-lowering medication?
Are you 18+ old with a history of heart or blood vessel disease?
Have you had a stroke, heart attack, or procedure to improve blood flow to the legs because of blocked arteries?
Do you have high LDL (“bad”) cholesterol?
People With a Prior Cardiovascular Event:
Are you taking cholesterol-lowering medication?
Are you a man 50+ with high LDL (“bad”) cholesterol?
Are you a women 55+ with high LDL (“bad”) cholesterol?
Have evidence of artery disease due to plaque buildup or other high-risk medical conditions?
What Should I Expect?
Screening Visit
Before you begin the study drug, AZD0780, or placebo, you will complete screening – including consent, medical history, and testing to determine if the study is right for you.
Randomization Visit
Participants are randomly assigned (50/50) to receive either the investigational study tablet or a matching placebo with no active medicine.
Treatment Phase
Should you qualify, your participation may last up to ~4.5 years. You’ll take either Investigational study drug (AZD0780) or matching placebo alongside your regular cholesterol medication. Participation is voluntary, and you can stop taking it at any time.
Start the Application:
See If You’re Eligible for the AZURE-Outcomes Study
Study Overview
The AstraZeneca “AZURE-Outcomes” study is testing a potential new oral, once a day, drug to learn whether it can help lower bad cholesterol and reduce the risk of heart and blood vessel disease in adults who:
- Have a history of heart disease or blood vessel disease OR
- Are at high risk for a first cardiovascular event, such as heart attack, stroke, or circulatory issues in the legs.
Qualified Participants May Receive:
- Reimbursement for their travel
- Study-related care at no cost.
Who Can Participate In The AZURE-Outcomes Study?
People With a Prior Cardiovascular Event:
- Are you taking cholesterol-lowering medication?
- Are you 18+ old with a history of heart or blood vessel disease?
- Have you had a stroke, heart attack, or procedure to improve blood flow to the legs because of blocked arteries?
- Do you have high LDL (“bad”) cholesterol?
People Who Have NOT Had a Cardiovascular Event, But are at High Risk:
- Are you taking cholesterol-lowering medication?
- Are you a man 50+ with high LDL (“bad”) cholesterol?
- Are you a women 55+ with high LDL (“bad”) cholesterol?
- Have evidence of artery disease due to plaque buildup or other high-risk medical conditions?
What Should I Expect?
Screening Visit
Before you begin the study drug, AZD0780, or placebo, you will complete screening – including consent, medical history, and testing to determine if the study is right for you.
Randomization Visit
Participants are randomly assigned (50/50) to receive either the investigational study tablet or a matching placebo with no active medicine.
Treatment Phase
Should you qualify, your participation may last up to ~4.5 years. You’ll take either Investigational study drug (AZD0780) or matching placebo alongside your regular cholesterol medication. Participation is voluntary, and you can stop taking it at any time.